Entries by Sumit Khetarpal

The Pathogens Behind Inflammatory Bowel Disease (IBD)

Over 2 million Americans suffer from chronic inflammatory bowel disease (IBD) which includes Crohn’s disease and Ulcerative colitis [1, 2]. These patients experience debilitating digestive symptoms like persistent diarrhea, rectal bleeding, and abdominal pain resulting in a detrimental impact on quality of life. While the exact cause of IBD is not fully understood, there is […]

Pathogens Behind SIBO And Limitations of Rifaximin

Rifaximin, a non-systemic antibiotic, is the standard of care for addressing SIBO [1]. However, it doesn’t work in over 50% of the patients [2]. The fortunate ones get their symptoms reduced but are rarely cured [3]. Further, 64% of the patients who benefit from Rifaximin relapse within a few months [4]. Clearly, a better solution […]

Principal Scientist – Strain Engineering

An estimated 700 million patients worldwide suffer from IBS. At Gutbiotics, our mission is to end IBS. We are developing genetically engineered bacteria that release antimicrobial peptides in the intestines and eliminate the IBS causing pathogens. In addition, the genetically engineered bacteria promote a healthy intestinal environment due to their probiotic nature.  We are seeking […]